Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005)

David M Nathan; Bernard Zinman; Patricia A Cleary; Jye-Yu C Backlund; Saul Genuth; Rachel Miller; Trevor J Orchard; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group; Timothy Lyons

doi:10.1001/archinternmed.2009.193

Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005)

David M Nathan, Bernard Zinman, Patricia A Cleary, Jye-Yu C Backlund, Saul Genuth, Rachel Miller, Trevor J Orchard, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Timothy Lyons

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

475 Citations (Scopus)

Abstract

Clinical treatment goals of type 1 diabetes mellitus (T1DM) have changed since the Diabetes Control and Complications Trial (DCCT) demonstrated reduced long-term complications with intensive diabetes therapy. There have been few longitudinal studies to describe the clinical course of T1DM in the age of intensive therapy. Our objective was to describe the current-day clinical course of T1DM.

Original language	English
Pages (from-to)	1307-16
Number of pages	10
Journal	Archives of Internal Medicine
Volume	169
Issue number	14
DOIs	https://doi.org/10.1001/archinternmed.2009.193
Publication status	Published - 27 Jul 2009

Keywords

Adolescent
Adult
Blood Glucose
Canada
Diabetes Complications
Diabetes Mellitus, Type 1
Diabetic Ketoacidosis
Humans
Hypoglycemia
Insulin
Longitudinal Studies
Middle Aged
Randomized Controlled Trials as Topic
United States
Weight Gain
Young Adult

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1001/archinternmed.2009.193

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Nathan, D. M., Zinman, B., Cleary, P. A., Backlund, J-Y. C., Genuth, S., Miller, R., Orchard, T. J., Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, & Lyons, T. (2009). Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005). Archives of Internal Medicine, 169(14), 1307-16. https://doi.org/10.1001/archinternmed.2009.193

Nathan, David M ; Zinman, Bernard ; Cleary, Patricia A et al. / Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration : the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005). In: Archives of Internal Medicine. 2009 ; Vol. 169, No. 14. pp. 1307-16.

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abstract = "Clinical treatment goals of type 1 diabetes mellitus (T1DM) have changed since the Diabetes Control and Complications Trial (DCCT) demonstrated reduced long-term complications with intensive diabetes therapy. There have been few longitudinal studies to describe the clinical course of T1DM in the age of intensive therapy. Our objective was to describe the current-day clinical course of T1DM.",

keywords = "Adolescent, Adult, Blood Glucose, Canada, Diabetes Complications, Diabetes Mellitus, Type 1, Diabetic Ketoacidosis, Humans, Hypoglycemia, Insulin, Longitudinal Studies, Middle Aged, Randomized Controlled Trials as Topic, United States, Weight Gain, Young Adult",

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Nathan, DM, Zinman, B, Cleary, PA, Backlund, J-YC, Genuth, S, Miller, R, Orchard, TJ, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group & Lyons, T 2009, 'Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005)', Archives of Internal Medicine, vol. 169, no. 14, pp. 1307-16. https://doi.org/10.1001/archinternmed.2009.193

Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration : the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005). / Nathan, David M; Zinman, Bernard; Cleary, Patricia A et al.

In: Archives of Internal Medicine, Vol. 169, No. 14, 27.07.2009, p. 1307-16.

Research output: Contribution to journal › Article › peer-review

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Nathan DM, Zinman B, Cleary PA, Backlund J-YC, Genuth S, Miller R et al. Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005). Archives of Internal Medicine. 2009 Jul 27;169(14):1307-16. doi: 10.1001/archinternmed.2009.193