Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005)

David M Nathan, Bernard Zinman, Patricia A Cleary, Jye-Yu C Backlund, Saul Genuth, Rachel Miller, Trevor J Orchard, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Timothy Lyons

Research output: Contribution to journalArticle

454 Citations (Scopus)

Abstract

Clinical treatment goals of type 1 diabetes mellitus (T1DM) have changed since the Diabetes Control and Complications Trial (DCCT) demonstrated reduced long-term complications with intensive diabetes therapy. There have been few longitudinal studies to describe the clinical course of T1DM in the age of intensive therapy. Our objective was to describe the current-day clinical course of T1DM.
Original languageEnglish
Pages (from-to)1307-16
Number of pages10
JournalArchives of Internal Medicine
Volume169
Issue number14
DOIs
Publication statusPublished - 27 Jul 2009

Keywords

  • Adolescent
  • Adult
  • Blood Glucose
  • Canada
  • Diabetes Complications
  • Diabetes Mellitus, Type 1
  • Diabetic Ketoacidosis
  • Humans
  • Hypoglycemia
  • Insulin
  • Longitudinal Studies
  • Middle Aged
  • Randomized Controlled Trials as Topic
  • United States
  • Weight Gain
  • Young Adult

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