Abstract
MTDSC is a software modification of the traditional DSC thermal analysis technique that allows
more accurate determination of the glass transition as well as measurement of the endothermic
relaxation that often accompanies the transition. The glass transition is an essential parameterboth
of the original frozen solution and of the end product. Measurement of endothermic relaxation
allows the determination of molecularrelaxation times in the freeze-dried product that may be
useful in predicting the effect of formulation variables and storage conditions on physical stability.
Original language | English |
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Pages (from-to) | 95-99 |
Number of pages | 5 |
Journal | European Journal of Parenteral and Pharmaceutical Sciences |
Volume | 6 |
Publication status | Published - Mar 2001 |