Molecular pathology - The value of an integrative approach

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24 Citations (Scopus)


Molecular Pathology (MP) is at the heart of modern diagnostics and translational research, but the controversy on how MP is best developed has not abated. The lack of a proper model or trained pathologists to support the diagnostic and research missions makes MP a rare commodity overall. Here we analyse the scientific and technology areas, in research and diagnostics, which are encompassed by MP of solid tumours; we highlight the broad overlap of technologies and analytical capabilities in tissue research and diagnostics; and we describe an integrated model that rationalizes technical know-how and pathology talent for both. The model is based on a single, accredited laboratory providing a single standard of high-quality for biomarker discovery, biomarker validation and molecular diagnostics.

Original languageEnglish
Pages (from-to)1163-8
Number of pages6
JournalMolecular oncology
Issue number7
Early online date12 Aug 2014
Publication statusPublished - 07 Oct 2014


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