Molecular pathomechanisms of Alzheimer's disease

B. Penke*, Z. Datki, C. Hetényi, Z. Molnár, I. Lengyel, K. Soós, M. Zarándi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

β-Amyloids are neurotoxic compounds produced in the brain and cause Alzheimer-type senile dementia. Their toxicity is in good correlation with their aggregation properties. Short peptide fragments of β-amyloid prevent Aβ-toxicity, probably by binding on the Aβ-aggregate surface.

Original languageEnglish
Pages (from-to)507-513
Number of pages7
JournalJournal of Molecular Structure: THEOCHEM
Volume666-667
DOIs
Publication statusPublished - 29 Dec 2003
Externally publishedYes

Keywords

  • β-Amyloid
  • Alzheimer's disease
  • Neurodegeneration
  • Neuroprotection

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Computational Theory and Mathematics
  • Atomic and Molecular Physics, and Optics

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