Abstract
Brains of mature and neonatal (P-3) rats were subjected to subcellular fractionation. Light membranes of P-3 contained more [3H]DAGO binding sites (40% of total μ sites vs 16% in adult) with greater sensitivity to GTP. Affinity labelling with [3H]DAGOCK revealed that the major subunit has a molecular weight of about 50 kDa in the synaptic as well as light membrane fractions.
Original language | English |
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Title of host publication | New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914 |
Editors | J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus |
Publisher | Elsevier B.V. |
Pages | 250 |
Number of pages | 1 |
ISBN (Print) | 044481213X |
Publication status | Published - 1990 |
Externally published | Yes |
Event | The International Narcotics Research Conference - Duration: 08 Jul 1989 → 13 Jul 1989 |
Conference
Conference | The International Narcotics Research Conference |
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Period | 08/07/1989 → 13/07/1989 |
ASJC Scopus subject areas
- General Medicine