Abstract
Despite continuous advances in analytical instrumentation, sample preparation remains one of the most crucial steps in an analytical process. In this regard, efforts have been made to improve selectivity during extraction and/or subsequent cleanup of sample extracts. Molecularly imprinted polymers (MIPs) are robust sorbents with molecular recognition abilities, provided by the presence of a template during their synthesis, and thus are excellent materials to provide selectivity in sample preparation. In this chapter, factors affecting the synthesis of MIPs and their subsequent performance in sample preparation procedures are discussed. The use of MIPs in solid-phase extraction and solid-phase microextraction as well as recent incorporation into other extraction techniques such as matrix solid-phase dispersion and stir-bar sorptive extraction, among others, is described. The advantages and drawbacks of each methodology as well as the future trends are discussed.
Original language | English |
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Title of host publication | Reference Module in Chemistry, Molecular Sciences and Chemical Engineering |
Publisher | Elsevier |
ISBN (Electronic) | 9780124095472 |
DOIs | |
Publication status | Published - 25 Nov 2024 |