Offshore structures are subjected to significant environmental loads from a combination of current, wind and wave action. Under such conditions, the directions of these environmental loads vary over the service life of the structure and therefore the cyclic lateral loading on the foundation also changes direction. The work reported in this article examines the effects of multidirectional loading on the performance of monopiles. Tests were carried out in a model sand bed and a mobile loading platform was manufactured to apply loading on the pile in various directions. Tests were also carried out where the cyclic loading was applied under both one-way and two-way loading. The observations indicate significant differences in the stiffness of monopiles between unidirectional and multidirectional lateral cyclic loading.. Multidirectional lateral cyclic loading generally results in higher displacements and lower stiffness compared to unidirectional loading, most likely due to shear deformation of a larger volume of soil mass adjacent to the pile.