Monospecific antibody to the haemagglutinin of measles virus

D E McFarlin; W J Bellini; E S Mingioli; T N Behar; A Trudgett

Monospecific antibody to the haemagglutinin of measles virus

D E McFarlin, W J Bellini, E S Mingioli, T N Behar, A Trudgett

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

A hybrid between a murine myeloma cell line and spleen cells from a mouse immunized with measles has been produced. Two stable clones produce antibody with identical immunochemical and biological properties. This antibody reacts with the 76,000 mol. wt. protein present in the lysates and on the surface of cells persistently infected with measles. It exhibits HAI and neutralizing activity.

Original language	English
Pages (from-to)	425-9
Number of pages	5
Journal	The Journal of general virology
Volume	48
Issue number	Pt 2
Publication status	Published - Jun 1980

Keywords

Animals
Antibodies, Viral
Antigen-Antibody Reactions
Cell Line
Epitopes
Hemagglutinins, Viral
Hybrid Cells
Immunoglobulin G
Measles virus
Mice
Neutralization Tests

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Monospecific antibody to the haemagglutinin of measles virus",

abstract = "A hybrid between a murine myeloma cell line and spleen cells from a mouse immunized with measles has been produced. Two stable clones produce antibody with identical immunochemical and biological properties. This antibody reacts with the 76,000 mol. wt. protein present in the lysates and on the surface of cells persistently infected with measles. It exhibits HAI and neutralizing activity.",

keywords = "Animals, Antibodies, Viral, Antigen-Antibody Reactions, Cell Line, Epitopes, Hemagglutinins, Viral, Hybrid Cells, Immunoglobulin G, Measles virus, Mice, Neutralization Tests",

author = "McFarlin, {D E} and Bellini, {W J} and Mingioli, {E S} and Behar, {T N} and A Trudgett",

year = "1980",

month = jun,

language = "English",

volume = "48",

pages = "425--9",

journal = "The Journal of general virology",

issn = "0022-1317",

publisher = "Society for General Microbiology",

number = "Pt 2",

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TY - JOUR

T1 - Monospecific antibody to the haemagglutinin of measles virus

AU - McFarlin, D E

AU - Bellini, W J

AU - Mingioli, E S

AU - Behar, T N

AU - Trudgett, A

PY - 1980/6

Y1 - 1980/6

N2 - A hybrid between a murine myeloma cell line and spleen cells from a mouse immunized with measles has been produced. Two stable clones produce antibody with identical immunochemical and biological properties. This antibody reacts with the 76,000 mol. wt. protein present in the lysates and on the surface of cells persistently infected with measles. It exhibits HAI and neutralizing activity.

AB - A hybrid between a murine myeloma cell line and spleen cells from a mouse immunized with measles has been produced. Two stable clones produce antibody with identical immunochemical and biological properties. This antibody reacts with the 76,000 mol. wt. protein present in the lysates and on the surface of cells persistently infected with measles. It exhibits HAI and neutralizing activity.

KW - Animals

KW - Antibodies, Viral

KW - Antigen-Antibody Reactions

KW - Cell Line

KW - Epitopes

KW - Hemagglutinins, Viral

KW - Hybrid Cells

KW - Immunoglobulin G

KW - Measles virus

KW - Mice

KW - Neutralization Tests

M3 - Article

C2 - 6156998

SN - 0022-1317

VL - 48

SP - 425

EP - 429

JO - The Journal of general virology

JF - The Journal of general virology

IS - Pt 2

ER -

Monospecific antibody to the haemagglutinin of measles virus

Abstract

Keywords

UN SDGs

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