Monospecific antibody to the haemagglutinin of measles virus

D E McFarlin, W J Bellini, E S Mingioli, T N Behar, A Trudgett

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Abstract

A hybrid between a murine myeloma cell line and spleen cells from a mouse immunized with measles has been produced. Two stable clones produce antibody with identical immunochemical and biological properties. This antibody reacts with the 76,000 mol. wt. protein present in the lysates and on the surface of cells persistently infected with measles. It exhibits HAI and neutralizing activity.
Original languageEnglish
Pages (from-to)425-9
Number of pages5
JournalThe Journal of general virology
Volume48
Issue numberPt 2
Publication statusPublished - Jun 1980

Keywords

  • Animals
  • Antibodies, Viral
  • Antigen-Antibody Reactions
  • Cell Line
  • Epitopes
  • Hemagglutinins, Viral
  • Hybrid Cells
  • Immunoglobulin G
  • Measles virus
  • Mice
  • Neutralization Tests

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  • Cite this

    McFarlin, D. E., Bellini, W. J., Mingioli, E. S., Behar, T. N., & Trudgett, A. (1980). Monospecific antibody to the haemagglutinin of measles virus. The Journal of general virology, 48(Pt 2), 425-9.