Multi-centre research in Australia: analysis of a recent National Health and Medical Research Council-funded project

Timothy J Kidd; Guy B Marks; Peter T P Bye; Claire E Wainwright; Philip J Robinson; Barbara R Rose; Colin Harbour; Scott C Bell; ACPinCF INVESTIGATORS

doi:10.1111/j.1440-1843.2009.01595.x

Multi-centre research in Australia: analysis of a recent National Health and Medical Research Council-funded project

Timothy J Kidd, Guy B Marks, Peter T P Bye, Claire E Wainwright, Philip J Robinson, Barbara R Rose, Colin Harbour, Scott C Bell, ACPinCF INVESTIGATORS

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: Human research ethics committees provide essential review of research projects to ensure the ethical conduct of human research. Several recent reports have highlighted a complex process for successful application for human research ethics committee approval, particularly for multi-centre studies. Limited resources are available for the execution of human clinical research in Australia and around the world.

METHODS: This report overviews the process of ethics approval for a National Health and Medical Research Council-funded multi-centre study in Australia, focussing on the time and resource implications of such applications in 2007 and 2008.

RESULTS: Applications were submitted to 16 hospital and two university human research ethics committees. The total time to gain final approval from each committee ranged between 13 and 77 days (median = 46 days); the entire process took 16 months to complete and the research officer's time was estimated to cost $A34 143.

CONCLUSIONS: Obstacles to timely human research ethics committee approval are reviewed, including recent, planned and potential initiatives that could improve the ethics approval of multi-centre research.

Original language	English
Pages (from-to)	1051-5
Number of pages	5
Journal	Respirology (Carlton, Vic.)
Volume	14
Issue number	7
DOIs	https://doi.org/10.1111/j.1440-1843.2009.01595.x
Publication status	Published - Sep 2009

Keywords

Australia
Biomedical Research
Ethics, Research
Humans
Multicenter Studies as Topic
National Health Programs

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title = "Multi-centre research in Australia: analysis of a recent National Health and Medical Research Council-funded project",

abstract = "BACKGROUND AND OBJECTIVE: Human research ethics committees provide essential review of research projects to ensure the ethical conduct of human research. Several recent reports have highlighted a complex process for successful application for human research ethics committee approval, particularly for multi-centre studies. Limited resources are available for the execution of human clinical research in Australia and around the world.METHODS: This report overviews the process of ethics approval for a National Health and Medical Research Council-funded multi-centre study in Australia, focussing on the time and resource implications of such applications in 2007 and 2008.RESULTS: Applications were submitted to 16 hospital and two university human research ethics committees. The total time to gain final approval from each committee ranged between 13 and 77 days (median = 46 days); the entire process took 16 months to complete and the research officer's time was estimated to cost $A34 143.CONCLUSIONS: Obstacles to timely human research ethics committee approval are reviewed, including recent, planned and potential initiatives that could improve the ethics approval of multi-centre research.",

keywords = "Australia, Biomedical Research, Ethics, Research, Humans, Multicenter Studies as Topic, National Health Programs",

author = "Kidd, {Timothy J} and Marks, {Guy B} and Bye, {Peter T P} and Wainwright, {Claire E} and Robinson, {Philip J} and Rose, {Barbara R} and Colin Harbour and Bell, {Scott C} and {ACPinCF INVESTIGATORS}",

year = "2009",

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Multi-centre research in Australia : analysis of a recent National Health and Medical Research Council-funded project. / Kidd, Timothy J; Marks, Guy B; Bye, Peter T P; Wainwright, Claire E; Robinson, Philip J; Rose, Barbara R; Harbour, Colin; Bell, Scott C; ACPinCF INVESTIGATORS.

In: Respirology (Carlton, Vic.), Vol. 14, No. 7, 09.2009, p. 1051-5.

Research output: Contribution to journal › Article › peer-review

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T1 - Multi-centre research in Australia

T2 - analysis of a recent National Health and Medical Research Council-funded project

AU - Kidd, Timothy J

AU - Marks, Guy B

AU - Bye, Peter T P

AU - Wainwright, Claire E

AU - Robinson, Philip J

AU - Rose, Barbara R

AU - Harbour, Colin

AU - Bell, Scott C

AU - ACPinCF INVESTIGATORS

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N2 - BACKGROUND AND OBJECTIVE: Human research ethics committees provide essential review of research projects to ensure the ethical conduct of human research. Several recent reports have highlighted a complex process for successful application for human research ethics committee approval, particularly for multi-centre studies. Limited resources are available for the execution of human clinical research in Australia and around the world.METHODS: This report overviews the process of ethics approval for a National Health and Medical Research Council-funded multi-centre study in Australia, focussing on the time and resource implications of such applications in 2007 and 2008.RESULTS: Applications were submitted to 16 hospital and two university human research ethics committees. The total time to gain final approval from each committee ranged between 13 and 77 days (median = 46 days); the entire process took 16 months to complete and the research officer's time was estimated to cost $A34 143.CONCLUSIONS: Obstacles to timely human research ethics committee approval are reviewed, including recent, planned and potential initiatives that could improve the ethics approval of multi-centre research.

AB - BACKGROUND AND OBJECTIVE: Human research ethics committees provide essential review of research projects to ensure the ethical conduct of human research. Several recent reports have highlighted a complex process for successful application for human research ethics committee approval, particularly for multi-centre studies. Limited resources are available for the execution of human clinical research in Australia and around the world.METHODS: This report overviews the process of ethics approval for a National Health and Medical Research Council-funded multi-centre study in Australia, focussing on the time and resource implications of such applications in 2007 and 2008.RESULTS: Applications were submitted to 16 hospital and two university human research ethics committees. The total time to gain final approval from each committee ranged between 13 and 77 days (median = 46 days); the entire process took 16 months to complete and the research officer's time was estimated to cost $A34 143.CONCLUSIONS: Obstacles to timely human research ethics committee approval are reviewed, including recent, planned and potential initiatives that could improve the ethics approval of multi-centre research.

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