Multiple Epidermolytic Acanthomas: Rare Vulval Lesions Which May be Mistaken for Viral Warts

Steven Irwin, Afzal Karim, Pamela McHenry, Sonya Hutchinson, Keith Miller, Jackie Jamison, Joseph Houghton, Glenn McCluggage

Research output: Contribution to journalArticle

Abstract

Epidermolytic acanthoma is a rare benign lesion that most often presents as a solitary or multiple small papular lesions on the trunk, face, limbs or external male genitalia. Only a small number of cases have been reported occurring on the vulva and clinically and histologically they may mimic and be misdiagnosed as viral warts. We report 2 cases of multiple epidermolytic acanthomas localized to the vulva. Molecular tests (in situ hybridization and polymerase chain reaction) showed no evidence of human papillomavirus infection and p16 staining was negative. We stress the need for pathologists to consider epidermolytic acanthoma in the differential diagnosis of multiple vulval lesions resembling viral warts.
Original languageEnglish
Pages (from-to)93-96
JournalInternational journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Volume39
Issue number1
DOIs
Publication statusPublished - Jan 2020

Fingerprint

Acanthoma
Warts
Vulva
Male Genitalia
Negative Staining
Papillomavirus Infections
Diagnostic Errors
In Situ Hybridization
Differential Diagnosis
Extremities
Polymerase Chain Reaction

Cite this

Irwin, Steven ; Karim, Afzal ; McHenry, Pamela ; Hutchinson, Sonya ; Miller, Keith ; Jamison, Jackie ; Houghton, Joseph ; McCluggage, Glenn. / Multiple Epidermolytic Acanthomas: Rare Vulval Lesions Which May be Mistaken for Viral Warts. In: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 2020 ; Vol. 39, No. 1. pp. 93-96.
@article{9ccc63aa6f394e5ebb3c6061ced2a268,
title = "Multiple Epidermolytic Acanthomas: Rare Vulval Lesions Which May be Mistaken for Viral Warts",
abstract = "Epidermolytic acanthoma is a rare benign lesion that most often presents as a solitary or multiple small papular lesions on the trunk, face, limbs or external male genitalia. Only a small number of cases have been reported occurring on the vulva and clinically and histologically they may mimic and be misdiagnosed as viral warts. We report 2 cases of multiple epidermolytic acanthomas localized to the vulva. Molecular tests (in situ hybridization and polymerase chain reaction) showed no evidence of human papillomavirus infection and p16 staining was negative. We stress the need for pathologists to consider epidermolytic acanthoma in the differential diagnosis of multiple vulval lesions resembling viral warts.",
author = "Steven Irwin and Afzal Karim and Pamela McHenry and Sonya Hutchinson and Keith Miller and Jackie Jamison and Joseph Houghton and Glenn McCluggage",
year = "2020",
month = "1",
doi = "10.1097/PGP.0000000000000570",
language = "English",
volume = "39",
pages = "93--96",
journal = "International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists",
issn = "0277-1691",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

Multiple Epidermolytic Acanthomas: Rare Vulval Lesions Which May be Mistaken for Viral Warts. / Irwin, Steven; Karim, Afzal; McHenry, Pamela; Hutchinson, Sonya; Miller, Keith; Jamison, Jackie; Houghton, Joseph; McCluggage, Glenn.

In: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 39, No. 1, 01.2020, p. 93-96.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Multiple Epidermolytic Acanthomas: Rare Vulval Lesions Which May be Mistaken for Viral Warts

AU - Irwin, Steven

AU - Karim, Afzal

AU - McHenry, Pamela

AU - Hutchinson, Sonya

AU - Miller, Keith

AU - Jamison, Jackie

AU - Houghton, Joseph

AU - McCluggage, Glenn

PY - 2020/1

Y1 - 2020/1

N2 - Epidermolytic acanthoma is a rare benign lesion that most often presents as a solitary or multiple small papular lesions on the trunk, face, limbs or external male genitalia. Only a small number of cases have been reported occurring on the vulva and clinically and histologically they may mimic and be misdiagnosed as viral warts. We report 2 cases of multiple epidermolytic acanthomas localized to the vulva. Molecular tests (in situ hybridization and polymerase chain reaction) showed no evidence of human papillomavirus infection and p16 staining was negative. We stress the need for pathologists to consider epidermolytic acanthoma in the differential diagnosis of multiple vulval lesions resembling viral warts.

AB - Epidermolytic acanthoma is a rare benign lesion that most often presents as a solitary or multiple small papular lesions on the trunk, face, limbs or external male genitalia. Only a small number of cases have been reported occurring on the vulva and clinically and histologically they may mimic and be misdiagnosed as viral warts. We report 2 cases of multiple epidermolytic acanthomas localized to the vulva. Molecular tests (in situ hybridization and polymerase chain reaction) showed no evidence of human papillomavirus infection and p16 staining was negative. We stress the need for pathologists to consider epidermolytic acanthoma in the differential diagnosis of multiple vulval lesions resembling viral warts.

U2 - 10.1097/PGP.0000000000000570

DO - 10.1097/PGP.0000000000000570

M3 - Article

VL - 39

SP - 93

EP - 96

JO - International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

JF - International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

SN - 0277-1691

IS - 1

ER -