Multiple site dioxygenase-catalysed cis-dihydroxylation of polycyclic azaarenes to yield a new class of bis-cis-diol metabolites

Derek Boyd, Narain Sharma, J.G. Carroll, Christopher Allen, D.A. Clarke, David Gibson

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The enhanced stability of new mono-cis-dihydrodiol bacterial metabolites of tricyclic azaarenes has facilitated the dioxygenase-catalysed formation and isolation of the corresponding bis-cis-dihydrodiols (cis-tetraols) and a three step chemoenzymatic route to the derived arene oxide mammalian metabolites.
Original languageEnglish
Pages (from-to)1201-1202
Number of pages2
JournalChemical Communications
VolumeNA
Issue number13
Publication statusPublished - 07 Jul 1999

ASJC Scopus subject areas

  • Chemistry(all)

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