Multiple site dioxygenase-catalysed cis-dihydroxylation of polycyclic azaarenes to yield a new class of bis-cis-diol metabolites

Derek Boyd; Narain Sharma; J.G. Carroll; Christopher Allen; D.A. Clarke; David Gibson

Multiple site dioxygenase-catalysed cis-dihydroxylation of polycyclic azaarenes to yield a new class of bis-cis-diol metabolites

Derek Boyd, Narain Sharma, J.G. Carroll, Christopher Allen, D.A. Clarke, David Gibson

Research output: Contribution to journal › Article › peer-review

Abstract

The enhanced stability of new mono-cis-dihydrodiol bacterial metabolites of tricyclic azaarenes has facilitated the dioxygenase-catalysed formation and isolation of the corresponding bis-cis-dihydrodiols (cis-tetraols) and a three step chemoenzymatic route to the derived arene oxide mammalian metabolites.

Original language	English
Pages (from-to)	1201-1202
Number of pages	2
Journal	Chemical Communications
Volume	NA
Issue number	13
Publication status	Published - 07 Jul 1999

ASJC Scopus subject areas

General Chemistry

Cite this

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title = "Multiple site dioxygenase-catalysed cis-dihydroxylation of polycyclic azaarenes to yield a new class of bis-cis-diol metabolites",

abstract = "The enhanced stability of new mono-cis-dihydrodiol bacterial metabolites of tricyclic azaarenes has facilitated the dioxygenase-catalysed formation and isolation of the corresponding bis-cis-dihydrodiols (cis-tetraols) and a three step chemoenzymatic route to the derived arene oxide mammalian metabolites.",

author = "Derek Boyd and Narain Sharma and J.G. Carroll and Christopher Allen and D.A. Clarke and David Gibson",

year = "1999",

month = jul,

day = "7",

language = "English",

volume = "NA",

pages = "1201--1202",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "13",

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TY - JOUR

T1 - Multiple site dioxygenase-catalysed cis-dihydroxylation of polycyclic azaarenes to yield a new class of bis-cis-diol metabolites

AU - Boyd, Derek

AU - Sharma, Narain

AU - Carroll, J.G.

AU - Allen, Christopher

AU - Clarke, D.A.

AU - Gibson, David

PY - 1999/7/7

Y1 - 1999/7/7

N2 - The enhanced stability of new mono-cis-dihydrodiol bacterial metabolites of tricyclic azaarenes has facilitated the dioxygenase-catalysed formation and isolation of the corresponding bis-cis-dihydrodiols (cis-tetraols) and a three step chemoenzymatic route to the derived arene oxide mammalian metabolites.

AB - The enhanced stability of new mono-cis-dihydrodiol bacterial metabolites of tricyclic azaarenes has facilitated the dioxygenase-catalysed formation and isolation of the corresponding bis-cis-dihydrodiols (cis-tetraols) and a three step chemoenzymatic route to the derived arene oxide mammalian metabolites.

M3 - Article

SN - 1359-7345

VL - NA

SP - 1201

EP - 1202

JO - Chemical Communications

JF - Chemical Communications

IS - 13

ER -

Multiple site dioxygenase-catalysed cis-dihydroxylation of polycyclic azaarenes to yield a new class of bis-cis-diol metabolites

Abstract

ASJC Scopus subject areas

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