Abstract
Vaginal rings releasing antiretrovirals - either alone or in combination with contraceptive progestins - are being developed for contraception and prevention of human immunodeficiency virus (HIV) transmission via vagina. However, hormonal contraceptives are associated with numerous side effects and contraindications, and many women are interested in using hormone-free contraceptives. The aim of this project is to develop multipurpose vaginal rings to release copper and/or zinc ions and dapivirine over a month for contraception and HIV prevention. Ring manufacture, swell testing, and in vitro drug release testing have been conducted. The experimental results obtained currently are encouraging and support the continued development of these ring formulations as a novel and interesting multipurpose prevention technology strategy.
| Original language | English |
|---|---|
| Article number | 1137 |
| Journal | British Journal of Pharmacy |
| Volume | 7 |
| Issue number | 2 |
| Early online date | 03 Nov 2022 |
| DOIs | |
| Publication status | Early online date - 03 Nov 2022 |
| Event | 13th APS PharmSci International Conference 2022 - Almac - Duration: 07 Sep 2022 → 09 Sep 2022 |
Keywords
- Management Science and Operations Research
- Mechanical Engineering
- Energy Engineering and Power Technology
Access to Document
- Multipurpose vaginal rings for HIV prevention and non-hormonal contraception
Copyright 2022 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.