N-H insertion reactions of rhodium carbenoids. Part 2. Preparation of N-substituted amino(phosphoryl)acetates (N-substituted phosphorylglycine esters).

L. Ferris, David Haigh, C.J. Moody

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)

Abstract

Rhodium(II) acetate-catalyzed reaction of Et 2-diazo-2-diethoxyphosphorylate, EtO2CC(:N2)PO(OEt)2, with carbamates, amides, ureas or anilines gives a range of N-substituted 2-amino-2-diethoxyphosphorylacetates, EtO2CCH(NHR1)PO(OEt)2 (where R1 = Boc, Cbz, acetyl, propionyl, pivaloyl, n-Pr, Ph and substituted Ph groups), by N-H insertion reaction of the intermediate rhodium carbenoid.
Original languageEnglish
Pages (from-to)2885-2888
Number of pages4
JournalJournal of the Chemical Society - Perkin Transactions 1
Volume-
Publication statusPublished - 1996

Fingerprint Dive into the research topics of 'N-H insertion reactions of rhodium carbenoids. Part 2. Preparation of N-substituted amino(phosphoryl)acetates (N-substituted phosphorylglycine esters).'. Together they form a unique fingerprint.

Cite this