Network biology: a direct approach to study biological function

Frank Emmert-Streib, G.V. Glazko

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

In this paper we discuss the dualism of gene networks and their role in systems biology. We argue that gene networks ( 1) can serve as a conceptual framework, forming a fundamental level of a phenomenological description, and ( 2) are a means to represent and analyze data. The latter point does not only allow a systems analysis but is even amenable for a direct approach to study biological function. Here we focus on the clarity of our main arguments and conceptual meaning of gene networks, rather than the causal inference of gene networks from data. (C) 2010 John Wiley & Sons, Inc. WIREs Syst Biol Med 2011 3 379-391 DOI: 10.1002/wsbm.134
Original languageEnglish
Pages (from-to)379-391
Number of pages13
JournalWILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE
Volume3
Issue number4
DOIs
Publication statusPublished - Jul 2011

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Medicine (miscellaneous)

Fingerprint

Dive into the research topics of 'Network biology: a direct approach to study biological function'. Together they form a unique fingerprint.

Cite this