NEUROPEPTIDES AND SEROTONIN IN THE CESTODE, PROTEOCEPHALUS-EXIGUUS - AN IMMUNOCYTOCHEMICAL STUDY

M.K.S. Gustafsson, H.P. Fagerholm, D W Halton, V. Hanzelova, Aaron Maule, M. Reuter, Christopher Shaw

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Neuropeptide F (NPF), RFamide and serotonin (5-HT) immunoreactivities have been detected in the nervous system of P. exiguus procercoids and adults, using an indirect immunocytochemical technique in conjunction with confocal scanning laser microscopy. The peptidergic nervous system of the procercoid is well developed, with two brain ganglia, three pairs of longitudinal nerve cords, transverse ring commissures and nerves in the suckers, all showing NPF-immunostaining. Strong NPF- and RF-immunostaining was observed in the CNS and PNS of the adult worm. The distribution patterns of the two neuropeptides were similar. Immunoreactivity for 5-HT was found only in the CNS.
Original languageEnglish
Pages (from-to)673-682
Number of pages10
JournalInternational Journal for Parasitology
Volume25
Publication statusPublished - 1995

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