Neuroprotective Diets Are Associated with Better Cognitive Function: The Health and Retirement Study

Claire T. McEvoy, Heidi Guyer, Kenneth M. Langa, Kristine Yaffe

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35 Citations (Scopus)
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Abstract

OBJECTIVES: To evaluate the association between theMediterranean diet (MedDiet) and the Mediterranean-DASH diet Intervention for Neurodegeneration Delay(MIND diet) and cognition in a nationally representativepopulation of older U.S. adults.DESIGN: Population-based cross-sectional study.SETTING: Health and Retirement Study.PARTICIPANTS: Community-dwelling older adults(N = 5,907; mean age 67.8  10.8).MEASUREMENTS: Adherence to dietary patterns wasdetermined from food frequency questionnaires using crite-ria determined a priori to generate diet scores for the Med-Diet (range 0–55) and MIND diet (range 0–15). Cognitiveperformance was measured using a composite test score ofglobal cognitive function (range 0–27). Linear regressionwas used to compare cognitive performance according totertiles of dietary pattern. Logistic regression was used toexamine the association between dietary patterns and clini-cally significant cognitive impairment. Models wereadjusted for age, sex, race, educational attainment, andother health and lifestyle covariates.RESULTS: Participants with mid (odds ratio (OR) = 0.85,95% confidence interval (CI) = 0.71–1.02, P = .08) andhigh (OR 0.65, 95% CI = 0.52–0.81, P < .001) MedDietscores were less likely to have poor cognitive performancethan those with low scores in fully adjusted models.Results for the MIND diet were similar. Higher scores ineach dietary pattern were independently associated withOBJECTIVES: To evaluate the association between theMediterranean diet (MedDiet) and the Mediterranean-DASH diet Intervention for Neurodegeneration Delay(MIND diet) and cognition in a nationally representativepopulation of older U.S. adults.DESIGN: Population-based cross-sectional study.SETTING: Health and Retirement Study.PARTICIPANTS: Community-dwelling older adults(N = 5,907; mean age 67.8  10.8).MEASUREMENTS: Adherence to dietary patterns wasdetermined from food frequency questionnaires using crite-ria determined a priori to generate diet scores for the Med-Diet (range 0–55) and MIND diet (range 0–15). Cognitiveperformance was measured using a composite test score ofglobal cognitive function (range 0–27). Linear regressionwas used to compare cognitive performance according totertiles of dietary pattern. Logistic regression was used toexamine the association between dietary patterns and clini-cally significant cognitive impairment. Models wereadjusted for age, sex, race, educational attainment, andother health and lifestyle covariates.RESULTS: Participants with mid (odds ratio (OR) = 0.85,95% confidence interval (CI) = 0.71–1.02, P = .08) andhigh (OR 0.65, 95% CI = 0.52–0.81, P < .001) MedDietscores were less likely to have poor cognitive performancethan those with low scores in fully adjusted models.Results for the MIND diet were similar. Higher scores ineach dietary pattern were independently associated with
Original languageEnglish
Number of pages6
JournalJournal of the American Geriatrics Society
Early online date25 Apr 2017
DOIs
Publication statusEarly online date - 25 Apr 2017

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  • Activities

    • 1 Participation in conference

    Alzheimer's Association International Conference 2017

    Claire McEvoy (Participant)

    15 Jul 2017

    Activity: Participating in or organising an event typesParticipation in conference

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