Neutrophils and eosinophils: clinical implications of their appearance, presence and disappearance in asthma and COPD.

Alison Watt, Bettina Schock, Madeleine Ennis

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.
Original languageEnglish
Article number16101518
Pages (from-to)415-423
Number of pages9
JournalCurrent drug targets. Inflammation and allergy
Volume4
Issue number4
DOIs
Publication statusPublished - Aug 2005

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Pharmacology

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