Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

J C Wilson, L J Murray, C M Hughes, A Black, L A Anderson

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)
163 Downloads (Pure)

Abstract

Background: Evidence for non-steroidal anti-inflammatory drugs (NSAIDs) preventing head and neck cancer (HNC) is inconclusive; however, there is some suggestion that aspirin may exert a protective effect.

Methods: Using data from the United States National Cancer Institute Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we examined the association between aspirin and ibuprofen use and HNC.

Results: Regular aspirin use was associated with a significant 22% reduction in HNC risk. No association was observed with regular ibuprofen use.

Conclusion: Aspirin may have potential as a chemopreventive agent for HNC, but further investigation is warranted.
Original languageEnglish
Pages (from-to)1178-1181
Number of pages4
JournalBritish Journal of Cancer
Volume108
Issue number5
Early online date28 Feb 2013
DOIs
Publication statusPublished - 2013

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Fingerprint

Dive into the research topics of 'Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer'. Together they form a unique fingerprint.

Cite this