Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

J C Wilson; L J Murray; C M Hughes; A Black; L A Anderson

doi:10.1038/bjc.2013.73

Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

J C Wilson, L J Murray, C M Hughes, A Black, L A Anderson

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Abstract

Background: Evidence for non-steroidal anti-inflammatory drugs (NSAIDs) preventing head and neck cancer (HNC) is inconclusive; however, there is some suggestion that aspirin may exert a protective effect.

Methods: Using data from the United States National Cancer Institute Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we examined the association between aspirin and ibuprofen use and HNC.

Results: Regular aspirin use was associated with a significant 22% reduction in HNC risk. No association was observed with regular ibuprofen use.

Conclusion: Aspirin may have potential as a chemopreventive agent for HNC, but further investigation is warranted.

Original language	English
Pages (from-to)	1178-1181
Number of pages	4
Journal	British Journal of Cancer
Volume	108
Issue number	5
Early online date	28 Feb 2013
DOIs	https://doi.org/10.1038/bjc.2013.73
Publication status	Published - 2013

ASJC Scopus subject areas

Cancer Research
Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/bjc.2013.73

Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
Copyright 2013 Cancer Research UK. This work is licensed under the Creative Commons Attribution NonCommercial-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-nc-sa/3.0/), which permits use, distribution and reproduction for non-commercial purposes, provided the author and source are cited and new creations are licensed under the identical terms.
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Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer: a systematic review.
Claire Wilson & Lesley Anderson
17/03/2011
1 item of Media coverage
Press/Media: Research

Cite this

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AB - Background: Evidence for non-steroidal anti-inflammatory drugs (NSAIDs) preventing head and neck cancer (HNC) is inconclusive; however, there is some suggestion that aspirin may exert a protective effect.Methods: Using data from the United States National Cancer Institute Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we examined the association between aspirin and ibuprofen use and HNC.Results: Regular aspirin use was associated with a significant 22% reduction in HNC risk. No association was observed with regular ibuprofen use.Conclusion: Aspirin may have potential as a chemopreventive agent for HNC, but further investigation is warranted.

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Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

Abstract

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Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer: a systematic review.

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