Novel methodology for the preparation and purification of oligonucleotides incorporating phosphorothiolate termini

Chemistry

• Oligonucleotide 100%
• Purification 100%
• Chemical Reaction 66%
• Oligomer 66%
• Chemical Reaction Product 33%
• Aqueous Solution 33%
• Derivatization 33%
• Silver 33%
• Phosphate 33%
• Hydroxyl Group 33%
• Phosphoramidite 33%
• Disulfide 33%
• Oligodeoxyribonucleotide 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Oligonucleotide 100%
• Oligomer 66%
• Phosphate 33%
• Disulfide 33%
• Silver 33%
• Hydroxyl Group 33%
• Phosphite 33%
• Reverse Phase High Performance Liquid Chromatography 33%
• Oligodeoxyribonucleotide 33%
• Phosphoramidous Acid 33%

Biochemistry, Genetics and Molecular Biology

• Copurification 100%
• Oligonucleotide 100%
• Solution and Solubility 33%
• Disulfide 33%
• Phosphate 33%
• Desalting 33%