Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).
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Davies, J., Malone, J., Boyd, D., Stein, B. K., Stevenson, C., Kumar, S., Lyle, J., Cosby, L., Sharma, N., & Hunter, A. P. (2002). Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane. Chemical Communications, 2002(13)(13), 1378-1379. https://doi.org/10.1039/b201418c