Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.

Jerry Davies; John Malone; Derek Boyd; B.K. Stein; C. Stevenson; S. Kumar; J. Lyle; L. Cosby; Narain Sharma; A.P. Hunter

doi:10.1039/b201418c

Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.

Jerry Davies, John Malone, Derek Boyd, B.K. Stein, C. Stevenson, S. Kumar, J. Lyle, L. Cosby, Narain Sharma, A.P. Hunter

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).

Original language	English
Pages (from-to)	1378-1379
Number of pages	2
Journal	Chemical Communications
Volume	2002(13)
Issue number	13
DOIs	https://doi.org/10.1039/b201418c
Publication status	Published - May 2002

ASJC Scopus subject areas

General Chemistry

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Cite this

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title = "Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.",

abstract = "Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).",

author = "Jerry Davies and John Malone and Derek Boyd and B.K. Stein and C. Stevenson and S. Kumar and J. Lyle and L. Cosby and Narain Sharma and A.P. Hunter",

year = "2002",

month = may,

doi = "10.1039/b201418c",

language = "English",

volume = "2002(13)",

pages = "1378--1379",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.

AU - Davies, Jerry

AU - Malone, John

AU - Boyd, Derek

AU - Stein, B.K.

AU - Stevenson, C.

AU - Kumar, S.

AU - Lyle, J.

AU - Cosby, L.

AU - Sharma, Narain

AU - Hunter, A.P.

PY - 2002/5

Y1 - 2002/5

N2 - Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).

AB - Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).

UR - http://www.scopus.com/inward/record.url?scp=0036087127&partnerID=8YFLogxK

U2 - 10.1039/b201418c

DO - 10.1039/b201418c

M3 - Article

SN - 1359-7345

VL - 2002(13)

SP - 1378

EP - 1379

JO - Chemical Communications

JF - Chemical Communications

IS - 13

ER -

Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.

Abstract

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