Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.

Jerry Davies, John Malone, Derek Boyd, B.K. Stein, C. Stevenson, S. Kumar, J. Lyle, L. Cosby, Narain Sharma, A.P. Hunter

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).
Original languageEnglish
Pages (from-to)1378-1379
Number of pages2
JournalChemical Communications
Volume2002(13)
Issue number13
DOIs
Publication statusPublished - May 2002

ASJC Scopus subject areas

  • Chemistry(all)

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    Davies, J., Malone, J., Boyd, D., Stein, B. K., Stevenson, C., Kumar, S., Lyle, J., Cosby, L., Sharma, N., & Hunter, A. P. (2002). Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane. Chemical Communications, 2002(13)(13), 1378-1379. https://doi.org/10.1039/b201418c