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Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.

  • Jerry Davies
  • , John Malone
  • , Derek Boyd
  • , B.K. Stein
  • , C. Stevenson
  • , S. Kumar
  • , J. Lyle
  • , L. Cosby
  • , Narain Sharma
  • , A.P. Hunter

Research output: Contribution to journalArticlepeer-review

Abstract

Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).
Original languageEnglish
Pages (from-to)1378-1379
Number of pages2
JournalChemical Communications
Volume2002(13)
Issue number13
DOIs
Publication statusPublished - May 2002

ASJC Scopus subject areas

  • General Chemistry

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