Nurses’ Sedation Practices During Weaning of Adults From Mechanical Ventilation in an Intensive Care Unit

Marta Barkowska, Sonia Labeau, Tom Schepens, Dominique Vandijck, Katrien Van de Vyver, Daphné Christiaens, Christelle Lizy, Bronagh Blackwood, Syijn I. Blot

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Background: Sedation and analgesia have an important impact on the outcome of patients treated with mechanical ventilation. International guidelines recommend use of sedation protocols to ensure best patient care.

Objective: To determine the sedation practice of intensive care nurses weaning adults from mechanical ventilation.

Methods: A cross-sectional survey with a self-administered questionnaire was used to determine sedation practices of Flemish critical care nurses during weaning. Consensus on content validity was achieved through a Delphi procedure among experts. Data were collected during the 32nd Annual Congress of the Flemish Society of Critical Care Nurses in Ghent, Belgium, December 2014.

Results: A total of 342 nurses were included in the study. Of these, 43.7% had a sedation protocol in their unit that was used by 61.8% of the respondents. Sedation protocols were more often available (P < .001) in academic hospitals (72%) than in general hospitals (41.5%). Sedatives were administered via continuous infusion with bolus doses if needed (81%). Level of sedation was assessed every 2 hours (56%), mostly via the Richmond Agitation-Sedation Scale (59.1%). Daily interruption of sedation was used by 16.5% of respondents. The biggest barriers to daily interruption were patient comfort (49.4%) and fear of respiratory worsening (46.6%).

Conclusions: A considerable discrepancy exists between international recommendations and actual sedation practices. Standardization of sedation practices across different institutions on a regional and national level may improve the quality of care.

Original languageEnglish
Pages (from-to)32-42
Number of pages11
JournalAmerican Journal of Critical Care
Issue number1
Publication statusPublished - 01 Jan 2018


  • Journal Article


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