On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance

P. M.  Dinh; L. Bouessel du Bourg; C.-Z. Gao; Bin Gu; L. Lacombe; M. McAllister; M. Smyth; G. Tribello; M. Vincendon; J. Kohanoff; P.-G. Reinhard; L. Sanche; E. Suraud

doi:10.1007/978-3-319-43030-0

On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance

P. M. Dinh, L. Bouessel du Bourg, C.-Z. Gao, Bin Gu, L. Lacombe, M. McAllister, M. Smyth, G. Tribello, M. Vincendon, J. Kohanoff, P.-G. Reinhard, L. Sanche, E. Suraud

School of Mathematics and Physics

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

1 Citation (Scopus)

Abstract

The two main products of ionizing radiation in biological tissues are electrons and radicals. The numerous secondary electrons are generated by ionisation in the molecules in the vicinity of DNA and are produced with a mean energy about 10 eV. These low-energy electrons can lead to DNA strand breaks via dissociative electron attachment and other mechanisms. The modelling of these phenomena requires, on the one hand, an explicit quantum description of the electrons of the target molecule (typically, a subunit of a DNA strand), and on the other hand, a realistic account of the DNA environment. This chapter reviews theoretical and computational approaches that have allowed us to study electron dynamics (excitation, ionization, transport and localization) in systems of biological interest.

Original language	English
Title of host publication	Nanoscale Insights into Ion-Beam Cancer Therapy
Editors	Andrey V. Solov'yov
Place of Publication	Switzerland
Publisher	Springer
Pages	277-309
Number of pages	33
ISBN (Electronic)	978-3-319-43030-0
ISBN (Print)	978-3-319-43028-7
DOIs	https://doi.org/10.1007/978-3-319-43030-0
Publication status	Published - 08 Dec 2016

Access to Document

10.1007/978-3-319-43030-0Licence: Unspecified

Cite this

Dinh, P. M., Bouessel du Bourg, L., Gao, C.-Z., Gu, B., Lacombe, L., McAllister, M., Smyth, M., Tribello, G., Vincendon, M., Kohanoff, J., Reinhard, P.-G., Sanche, L., & Suraud, E. (2016). On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance. In A. V. Solov'yov (Ed.), Nanoscale Insights into Ion-Beam Cancer Therapy (pp. 277-309). Springer. https://doi.org/10.1007/978-3-319-43030-0

@inbook{d31ea63e84e34a5bb9f2468ab903a92d,

title = "On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance",

abstract = "The two main products of ionizing radiation in biological tissues are electrons and radicals. The numerous secondary electrons are generated by ionisation in the molecules in the vicinity of DNA and are produced with a mean energy about 10 eV. These low-energy electrons can lead to DNA strand breaks via dissociative electron attachment and other mechanisms. The modelling of these phenomena requires, on the one hand, an explicit quantum description of the electrons of the target molecule (typically, a subunit of a DNA strand), and on the other hand, a realistic account of the DNA environment. This chapter reviews theoretical and computational approaches that have allowed us to study electron dynamics (excitation, ionization, transport and localization) in systems of biological interest.",

author = "Dinh, {P. M.} and {Bouessel du Bourg}, L. and C.-Z. Gao and Bin Gu and L. Lacombe and M. McAllister and M. Smyth and G. Tribello and M. Vincendon and J. Kohanoff and P.-G. Reinhard and L. Sanche and E. Suraud",

year = "2016",

month = dec,

day = "8",

doi = "10.1007/978-3-319-43030-0",

language = "English",

isbn = "978-3-319-43028-7",

pages = "277--309",

editor = "Solov'yov, {Andrey V.}",

booktitle = "Nanoscale Insights into Ion-Beam Cancer Therapy",

publisher = "Springer",

}

Dinh, PM, Bouessel du Bourg, L, Gao, C-Z, Gu, B, Lacombe, L, McAllister, M, Smyth, M, Tribello, G, Vincendon, M, Kohanoff, J, Reinhard, P-G, Sanche, L & Suraud, E 2016, On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance. in AV Solov'yov (ed.), Nanoscale Insights into Ion-Beam Cancer Therapy. Springer, Switzerland, pp. 277-309. https://doi.org/10.1007/978-3-319-43030-0

TY - CHAP

T1 - On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance

AU - Dinh, P. M.

AU - Bouessel du Bourg, L.

AU - Gao, C.-Z.

AU - Gu, Bin

AU - Lacombe, L.

AU - McAllister, M.

AU - Smyth, M.

AU - Tribello, G.

AU - Vincendon, M.

AU - Kohanoff, J.

AU - Reinhard, P.-G.

AU - Sanche, L.

AU - Suraud, E.

PY - 2016/12/8

Y1 - 2016/12/8

N2 - The two main products of ionizing radiation in biological tissues are electrons and radicals. The numerous secondary electrons are generated by ionisation in the molecules in the vicinity of DNA and are produced with a mean energy about 10 eV. These low-energy electrons can lead to DNA strand breaks via dissociative electron attachment and other mechanisms. The modelling of these phenomena requires, on the one hand, an explicit quantum description of the electrons of the target molecule (typically, a subunit of a DNA strand), and on the other hand, a realistic account of the DNA environment. This chapter reviews theoretical and computational approaches that have allowed us to study electron dynamics (excitation, ionization, transport and localization) in systems of biological interest.

AB - The two main products of ionizing radiation in biological tissues are electrons and radicals. The numerous secondary electrons are generated by ionisation in the molecules in the vicinity of DNA and are produced with a mean energy about 10 eV. These low-energy electrons can lead to DNA strand breaks via dissociative electron attachment and other mechanisms. The modelling of these phenomena requires, on the one hand, an explicit quantum description of the electrons of the target molecule (typically, a subunit of a DNA strand), and on the other hand, a realistic account of the DNA environment. This chapter reviews theoretical and computational approaches that have allowed us to study electron dynamics (excitation, ionization, transport and localization) in systems of biological interest.

U2 - 10.1007/978-3-319-43030-0

DO - 10.1007/978-3-319-43030-0

M3 - Chapter (peer-reviewed)

SN - 978-3-319-43028-7

SP - 277

EP - 309

BT - Nanoscale Insights into Ion-Beam Cancer Therapy

A2 - Solov'yov, Andrey V.

PB - Springer

CY - Switzerland

ER -

On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance

Abstract

Access to Document

Fingerprint

Cite this