Optimising low molecular weight hydrogels for automated 3D printing

Michael C. Nolan; Ana M. Fuentes-Caparrós; Bart Dietrich; Michael Barrow; Emily R. Cross; Markus Bleuel; Stephen M. King; Dave J. Adams

doi:10.1039/C7SM01694H

Optimising low molecular weight hydrogels for automated 3D printing

Michael C. Nolan, Ana M. Fuentes-Caparrós, Bart Dietrich, Michael Barrow, Emily R. Cross, Markus Bleuel, Stephen M. King, Dave J. Adams

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

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Abstract

Hydrogels prepared from low molecular weight gelators (LMWGs) are formed as a result of hierarchical intermolecular interactions between gelators to form fibres, and then further interactions between the self-assembled fibres via physical entanglements, as well as potential branching points. These interactions can allow hydrogels to recover quickly after a high shear rate has been applied. There are currently limited design rules describing which types of morphology or rheological properties are required for a LMWG hydrogel to be used as an effective, printable gel. By preparing hydrogels with different types of fibrous network structures, we have been able to understand in more detail the morphological type which gives rise to a 3D-printable hydrogel using a range of techniques, including rheology, small angle scattering and microscopy.

Original language	English
Pages (from-to)	8426-8432
Number of pages	7
Journal	Soft Matter
Volume	13
Issue number	45
DOIs	https://doi.org/10.1039/C7SM01694H
Publication status	Published - 26 Oct 2017

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10.1039/C7SM01694H

Optimising low molecular weight hydrogels for automated 3D printing
© 2020 The Authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 2.78 MBLicence: CC BY

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title = "Optimising low molecular weight hydrogels for automated 3D printing",

abstract = "Hydrogels prepared from low molecular weight gelators (LMWGs) are formed as a result of hierarchical intermolecular interactions between gelators to form fibres, and then further interactions between the self-assembled fibres via physical entanglements, as well as potential branching points. These interactions can allow hydrogels to recover quickly after a high shear rate has been applied. There are currently limited design rules describing which types of morphology or rheological properties are required for a LMWG hydrogel to be used as an effective, printable gel. By preparing hydrogels with different types of fibrous network structures, we have been able to understand in more detail the morphological type which gives rise to a 3D-printable hydrogel using a range of techniques, including rheology, small angle scattering and microscopy.",

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AU - Bleuel, Markus

AU - King, Stephen M.

AU - Adams, Dave J.

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N2 - Hydrogels prepared from low molecular weight gelators (LMWGs) are formed as a result of hierarchical intermolecular interactions between gelators to form fibres, and then further interactions between the self-assembled fibres via physical entanglements, as well as potential branching points. These interactions can allow hydrogels to recover quickly after a high shear rate has been applied. There are currently limited design rules describing which types of morphology or rheological properties are required for a LMWG hydrogel to be used as an effective, printable gel. By preparing hydrogels with different types of fibrous network structures, we have been able to understand in more detail the morphological type which gives rise to a 3D-printable hydrogel using a range of techniques, including rheology, small angle scattering and microscopy.

AB - Hydrogels prepared from low molecular weight gelators (LMWGs) are formed as a result of hierarchical intermolecular interactions between gelators to form fibres, and then further interactions between the self-assembled fibres via physical entanglements, as well as potential branching points. These interactions can allow hydrogels to recover quickly after a high shear rate has been applied. There are currently limited design rules describing which types of morphology or rheological properties are required for a LMWG hydrogel to be used as an effective, printable gel. By preparing hydrogels with different types of fibrous network structures, we have been able to understand in more detail the morphological type which gives rise to a 3D-printable hydrogel using a range of techniques, including rheology, small angle scattering and microscopy.

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DO - 10.1039/C7SM01694H

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Optimising low molecular weight hydrogels for automated 3D printing

Abstract

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