Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate

M.J. Slater, E.M. Amphlett, D.M. Andrews, G. Bravi, G. Burton, A.G. Cheasty, J.A. Corfield, M.R. Ellis, R.H. Fenwick, S. Fernandes, R. Guidetti, David Haigh, C.D. Hartley, P.D. Howes, D.L. Jackson, R.L. Jarvest, V.L.H. Lovegrove, K.J. Medhurst, N.R. Parry, H. PriceP. Shah, O.M.P. Singh, R. Stocker, P. Thommes, C. Wilkinson, A. Wonacott