Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block

M. Shields, M. Giovannelli, Rajinder Mirakhur, I. Moppett, J. Adams, Y. Hermens

Research output: Contribution to journalArticlepeer-review

145 Citations (Scopus)

Abstract

Background. Org 25969 is a cyclodextrin compound designed to reverse a rocuronium-induced neuromuscular block. The aim of this study was to explore the efficacy, dose-response relation and safety of Org 25969 for reversal of a prolonged rocuronium-induced neuromuscular block. Methods. Thirty anaesthetised adult patients received rocuronium 0.6mg kg as an initial dose followed by increments to maintain a deep block at level of
Original languageEnglish
Pages (from-to)36-43
Number of pages8
JournalBritish Journal of Anaesthesia
Volume96
Issue number1
Publication statusPublished - Jan 2006

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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