Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block

M. Shields; M. Giovannelli; Rajinder Mirakhur; I. Moppett; J. Adams; Y. Hermens

Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block

M. Shields, M. Giovannelli, Rajinder Mirakhur, I. Moppett, J. Adams, Y. Hermens

Research output: Contribution to journal › Article › peer-review

Abstract

Background. Org 25969 is a cyclodextrin compound designed to reverse a rocuronium-induced neuromuscular block. The aim of this study was to explore the efficacy, dose-response relation and safety of Org 25969 for reversal of a prolonged rocuronium-induced neuromuscular block. Methods. Thirty anaesthetised adult patients received rocuronium 0.6mg kg as an initial dose followed by increments to maintain a deep block at level of

Original language	English
Pages (from-to)	36-43
Number of pages	8
Journal	British Journal of Anaesthesia
Volume	96
Issue number	1
Publication status	Published - Jan 2006

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Cite this

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abstract = "Background. Org 25969 is a cyclodextrin compound designed to reverse a rocuronium-induced neuromuscular block. The aim of this study was to explore the efficacy, dose-response relation and safety of Org 25969 for reversal of a prolonged rocuronium-induced neuromuscular block. Methods. Thirty anaesthetised adult patients received rocuronium 0.6mg kg as an initial dose followed by increments to maintain a deep block at level of",

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AU - Giovannelli, M.

AU - Mirakhur, Rajinder

AU - Moppett, I.

AU - Adams, J.

AU - Hermens, Y.

PY - 2006/1

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AB - Background. Org 25969 is a cyclodextrin compound designed to reverse a rocuronium-induced neuromuscular block. The aim of this study was to explore the efficacy, dose-response relation and safety of Org 25969 for reversal of a prolonged rocuronium-induced neuromuscular block. Methods. Thirty anaesthetised adult patients received rocuronium 0.6mg kg as an initial dose followed by increments to maintain a deep block at level of

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Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block

Abstract

ASJC Scopus subject areas

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