Oxidation of N-(4-methoxybenzyl)-2-pyrrolidinones to N-(4-methoxybenzoyl)-2-pyrrolidinones. Rapid entry to optically active Aniracetam analogues.

H McAlonan, JP Murphy, PJ Stevenson, AB Treacy

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Oxidation of readily available N-(4-methoxybenzyl)-5-alkylpyrrolidin-2-ones to the corresponding N-(4-methoxybenzoyl)-5-alkylpyrrolidin-2-ones gives direct access to enantiomerically pure 5-alkyl analogues of the cognition activating agent Aniracetam. Copyright (C) 1996 Elsevier Science Ltd

Original languageEnglish
Pages (from-to)12521-12528
Number of pages8
JournalTetrahedron
Volume52
Issue number38
Publication statusPublished - 16 Sep 1996

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