Abstract
Oxidative stress may increase lung permeability by upregulation of matrix-metalloproteinase-9 (MMP-8), a type-IV collagenase that can disrupt alveolar basement membranes. We have compared a marker of oxidative stress (protein carbonyl residues) with levels of MMP-8 and its inhibitor, tissue inhibitor of metalloproteinase-1 (TIMP-1), in bronchoalveolar lavage samples from newborn babies. Bronchoalveolar lavage samples (n = 87, two from each time point) were taken in the first 6 postnatal days from 41 ventilated babies: 18 of
Original language | English |
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Pages (from-to) | 29-33 |
Number of pages | 5 |
Journal | Pediatric Research |
Volume | 50 |
Issue number | 1 I |
Publication status | Published - 2001 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health