Abstract
A wide range of palladium catalysed regio- and stereo-specific 5-, 6- and 7-exo-dig mono-, bis- and tris-cyclisation processes of aryl and vinyl halides and allylic acetates are described. The mono- and bis-cyclisation processes terminate in hydride capture from piperidine-formic acid or sodium formate. Addition of TI2CO3 results in alkyne-allene isomerisation and leads, after cyclisation, to 1,3-dienes which give Diels-Alder adducts in good yield. Copyright (C) 1996 Elsevier Science Ltd
Original language | English |
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Pages (from-to) | 11479-11502 |
Number of pages | 24 |
Journal | Tetrahedron |
Volume | 52 |
Issue number | 35 |
Publication status | Published - 26 Aug 1996 |
Event | 1st International Symposium on Cascade Reactions - LEEDS, United Kingdom Duration: 01 Jan 1994 → … |
Keywords
- FUNCTIONALLY-SUBSTITUTED ARYL
- INTRAMOLECULAR HECK REACTIONS
- REGIOSPECIFIC CYCLIZATION
- DEHYDROGENATION ROUTE
- COUPLING REACTION
- EXCHANGE-REACTION
- INTERNAL ALKYNES
- TERTIARY-AMINES
- ALLYLIC AMINES
- ION CAPTURE