Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones

Kate L. Baddeley; Qun Cao; Mark J. Muldoon; Matthew J. Cook

doi:10.1002/chem.201500862

Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones

Kate L. Baddeley, Qun Cao, Mark J. Muldoon, Matthew J. Cook

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.

Original language	English
Pages (from-to)	7726-7730
Number of pages	5
Journal	Chemistry - A European Journal
Volume	21
Issue number	21
Early online date	27 Mar 2015
DOIs	https://doi.org/10.1002/chem.201500862
Publication status	Published - 18 May 2015

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10.1002/chem.201500862

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Mark Muldoon
- m.j.muldoon@qub.ac.uk
Person: Academic

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title = "Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones",

abstract = "A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.",

author = "Baddeley, {Kate L.} and Qun Cao and Muldoon, {Mark J.} and Cook, {Matthew J.}",

year = "2015",

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AU - Baddeley, Kate L.

AU - Cao, Qun

AU - Muldoon, Mark J.

AU - Cook, Matthew J.

PY - 2015/5/18

Y1 - 2015/5/18

N2 - A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.

AB - A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.

U2 - 10.1002/chem.201500862

DO - 10.1002/chem.201500862

M3 - Article

VL - 21

SP - 7726

EP - 7730

JO - Chemistry-a European Journal

JF - Chemistry-a European Journal

SN - 0947-6539

IS - 21

ER -

Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones

Abstract

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Mark Muldoon

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