Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones

Kate L. Baddeley, Qun Cao, Mark J. Muldoon, Matthew J. Cook

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.
Original languageEnglish
Pages (from-to)7726-7730
Number of pages5
JournalChemistry - A European Journal
Issue number21
Early online date27 Mar 2015
Publication statusPublished - 18 May 2015


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