Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones

Kate L. Baddeley; Qun Cao; Mark J. Muldoon; Matthew J. Cook

doi:10.1002/chem.201500862

Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones

Kate L. Baddeley, Qun Cao, Mark J. Muldoon, Matthew J. Cook

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.

Original language	English
Pages (from-to)	7726-7730
Number of pages	5
Journal	Chemistry - A European Journal
Volume	21
Issue number	21
Early online date	27 Mar 2015
DOIs	https://doi.org/10.1002/chem.201500862
Publication status	Published - 18 May 2015

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Baddeley, K. L., Cao, Q., Muldoon, M. J., & Cook, M. J. (2015). Palladium-Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones. Chemistry - A European Journal, 21(21), 7726-7730. https://doi.org/10.1002/chem.201500862

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abstract = "A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.",

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AB - A palladium-catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone. The products are formed in good to excellent yields with a very high level of chemoselectivity and functional group tolerance. Mechanistic studies confirm that the reaction proceeds by a Wacker-type mechanism.

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DO - 10.1002/chem.201500862

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10.1002/chem.201500862