Peptide-directed assembly of functional supramolecular polymers for biomedical applications: electroactive molecular tongue-twisters (oligoalanine–oligoaniline–oligoalanine) for electrochemically enhanced drug delivery

John G. Hardy, Megan N. Amend, Sydney Geissler, Vincent M. Lynch, Christine E. Schmidt

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)
171 Downloads (Pure)

Abstract

We report the preparation and characterization of films of electroactive supramolecular polymers based on non-electroactive oligoalanines and electroactive oligoanilines. Fibroblasts adhered to and proliferated on the films, and the delivery of the clinically relevant anti-inflammatory drug dexamethasone phosphate could be enhanced upon the application of an electrical stimulus.
Original languageEnglish
Pages (from-to)5005-5009
Number of pages5
JournalJournal of Materials Chemistry B
Volume3
Issue number25
Early online date08 Jun 2015
DOIs
Publication statusPublished - 2015
Externally publishedYes

Keywords

  • SUPRAMOLECULAR CHEMISTRY
  • SUPRAMOLECULAR POLYMERS
  • BIOMATERIALS
  • Drug delivery

ASJC Scopus subject areas

  • Chemistry (miscellaneous)
  • Biomaterials

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