Abstract
Perifosine is an orally active alkylphospholipid analog, which has shown anti-tumor activity in a variety of cancers by inhibition of AKT phosphorylation. The objective of the current study was to evaluate its efficacy in in vitro models of human endometrial cancer.
Original language | English |
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Pages (from-to) | 64-9 |
Number of pages | 6 |
Journal | European journal of obstetrics, gynecology, and reproductive biology |
Volume | 141 |
Issue number | 1 |
DOIs | |
Publication status | Published - Nov 2008 |
Keywords
- Antineoplastic Agents
- Antineoplastic Combined Chemotherapy Protocols
- Apoptosis
- Cell Line, Tumor
- Cisplatin
- Endometrial Neoplasms
- Female
- Humans
- Phosphorylation
- Phosphorylcholine
- Proto-Oncogene Proteins c-akt