Phagocytic and serum killing of capsulate and non-capsulate Bacteroides fragilis

J H Reid, S Patrick

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The relative susceptibilities of capsulate and non- capsulate variants of Bacteroides fragilis to serum and phagocytic killing were investigated. The capsule of B. fragilis did not confer resistance to serum killing. Phagocytic killing of non- capsulate B. fragilis occurred at bacterial concentrations of 1 X 10(6) and 1 X 10(7) cfu/ml. Capsulate B. fragilis organisms were also phagocytosed and killed at a concentration of 1 X 10(6) cfu/ml, but phagocytosis and killing were impaired at a concentration of 1 X 10(7) cfu/ml.
Original languageEnglish
Pages (from-to)247-57
Number of pages11
JournalJournal of Medical Microbiology
Volume17
Issue number3
Publication statusPublished - 1984

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