Abstract
The rapid increase in pathogenic microorganisms with antimicrobial resistant profiles has become a significant public health problem globally. The management of this issue using conventional antimicrobial preparations frequently results in an increase in pathogen resistance and a shortage of effective antimicrobials for future use against the same pathogens. In this review, we discuss the emergence of AMR and argue for the importance of addressing this issue by discovering novel synthetic or naturally occurring antibacterial compounds and providing insights into the application of various drug delivery approaches, delivered through numerous routes, in comparison with conventional delivery systems. In addition, we discuss the effectiveness of these delivery systems in different types of infectious diseases associated with antimicrobial resistance. Finally, future considerations in the development of highly effective antimicrobial delivery systems to combat an-timicrobial resistance are presented.
| Original language | English |
|---|---|
| Article number | 981 |
| Journal | Antibiotics |
| Volume | 10 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 14 Aug 2021 |
Bibliographical note
Publisher Copyright:© 2021 by the authors. Li-censee MDPI, Basel, Switzerland.
Keywords
- Antimicrobial resistance
- Antimicrobials
- Drug delivery
- Pharmaceutical preparations
ASJC Scopus subject areas
- Microbiology
- Biochemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Microbiology (medical)
- Infectious Diseases
- Pharmacology (medical)
Access to Document
- Pharmaceutical approaches on antimicrobial resistance: prospects and challenges
Copyright 2022 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.