Pharmaceutical strategies towards optimising polypharmacy in older people

Carmel M. Hughes, Cathal A. Cadogan, Deborah Patton, Cristín A. Ryan

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


This paper focuses on the issue of polypharmacy in older people and potential pharmaceutical strategies to optimize the use of multiple medicines. Although polypharmacy has long been viewed negatively, increasing emphasis is being placed on the difference between appropriate and inappropriate polypharmacy. This is largely being driven by the increasing prevalence of multimorbidity and the use of evidence-based guidelines. In this paper, we outline a number of key considerations that are pertinent to optimizing polypharmacy, notably prescribing appropriate polypharmacy, pharmaceutical formulations, the involvement of older people in clinical trials and patient adherence.
Original languageEnglish
Number of pages6
JournalInternational Journal of Pharmaceutics
Early online date26 Feb 2016
Publication statusEarly online date - 26 Feb 2016


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