Pharmacist-independent prescriber deprescribing in UK care homes: Contextual factors associated with increased activity

Mohammed Alharthi, Sion Scott, David Phillip Alldred, Richard Holland, Carmel Hughes, Linda Birt, Jeanette Blacklock, Christine Bond, Allan Clark, David Wright

Research output: Contribution to journalArticlepeer-review


The Care Home Independent Pharmacist Prescriber Study (CHIPPS) process evaluation hypothesized that contextual factors influenced the likelihood of deprescribing by pharmacist-independent prescribers. The aim of this paper is to test this hypothesis. From CHIPPS study data, medications deprescribed totalled 284 for 370 residents in UK care homes. Regression analysis was used to describe the relationship between the number of medicines stopped and contextual factors (number of residents cared for, pharmacist employment within associated medical practice, previous care home experience, hours active within trial, years' experience as a pharmacist and as a prescriber). Number of residents and pharmacist-independent prescriber employment within a medical practice were positive predictors of deprescribing. Previous experiences were not related to deprescribing likelihood. Increasing the number of residents increases the opportunity for deprescribing and therefore this relationship is intuitive. The location within a medical practice is an interesting finding that requires further exploration to understand its exact nature.
Original languageEnglish
JournalBritish Journal of Clinical Pharmacology
Early online date23 Dec 2022
Publication statusEarly online date - 23 Dec 2022


  • deprescription
  • long-term care facilities
  • medication review
  • medicines optimization
  • nursing home
  • polypharmacy
  • residential home


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