Abstract
The aim of the present study was to investigate the responses of phase I and II biotransformation enzymes and levels of PAHs in the Mediterranean mussel (Mytilus galloprovincialis, Lamarck, 1819) collected from three sites at different distance from an oil refinery. Phase I enzyme activities as NAD(P)H-cyt c red, NADH ferry red, B(a)PMO and phase II as UDPGT. GST were measured in digestive gland while 16 PAHs (US-EPA) in whole soft tissue. An added value to the data obtained in the present study rely on the RDA analysis which showed close correlations between PAHs levels and phase I enzyme activities in mussels collected in front of the refinery. And again a significant spatial correlation between B(a)P levels and NADPH-cyt c red activities was observed using linear models. No differences among sites for B(a) PMO and phase II GST activities were observed, while the application of UDPGT as biomarkers requires further investigation. (C) 2012 Elsevier Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 29-36 |
| Number of pages | 8 |
| Journal | Marine environmental research |
| Volume | 79 |
| DOIs | |
| Publication status | Published - Aug 2012 |
Keywords
- GLUTATHIONE S-TRANSFERASES
- Pollution monitoring
- Oil refinery
- EDULIS-L
- B(a)P
- ADRIATIC SEA
- COMMON MUSSEL
- Hydrocarbons
- NADPH cytochrome c reductase
- LITTORINA-LITTOREA L
- CAGED MUSSELS
- CYTOCHROME P450-DEPENDENT MONOOXYGENASE
- DIGESTIVE GLAND
- Cytochrome P450
- Biomarker
- Mussel
- ENVIRONMENTAL CONTAMINATION
- DNA-ADDUCTS
- GST