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Photocontrolled Binding and Binding-Controlled Photochromism within Anthracene-Modified DNA

  • Jack Manchester
  • , Dario M. Bassani
  • , Jean-Louise H. A. Duprey
  • , Luciano Giordano
  • , Joseph S. Vyle
  • , Zheng-yun Zhao
  • , James H. R. Tucker

Research output: Contribution to journal › Article › peer-review

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Abstract

Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.
Original languageEnglish
Pages (from-to)10791-10794
Number of pages4
JournalJournal of the American Chemical Society
Volume134
Issue number26
Early online date13 Jun 2012
DOIs
Publication statusPublished - 2012

ASJC Scopus subject areas

  • General Chemistry
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

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