PHYSICAL FACTORS AFFECTING THE SPORICIDAL ACTIVITY OF CHLORHEXIDINE GLUCONATE

David Jones, A.M. Loftus, Sean Gorman

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The effects of pH and indirect ultrasonication on the cidal activity of aqueous and alcoholic solutions of chlorhexidine gluconate against Bacillus subtilis spores were examined. At moderately elevated temperatures, increasing pH enhanced sporicidal activity. pH markedly enhanced the sporicidal activity between indirect ultrasound and chlorhexidine. 'Alcoholic' chlorhexidine gluconate was more sporicidal than its aqueous counterpart.
Original languageEnglish
Pages (from-to)247-250
Number of pages4
JournalInternational Journal of Pharmaceutics
Volume119
Publication statusPublished - 1995

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