Abstract
Formulation of Celecoxib into solid dosage forms is difficult due to the physical properties of the drug powder. However for the first time, this paper reports on the drug delivery characteristics glass solutions of celecoxib and polyvinylpyrrolidone prepared by hot melt extrusion, together with use of supercritical carbon dioxide to achieve a porous structure, in order to achieve a stable and enhanced drug release.
| Original language | English |
|---|---|
| Pages (from-to) | 1580-1590 |
| Number of pages | 11 |
| Journal | Journal of Pharmacy and Pharmacology |
| Volume | 62 |
| DOIs | |
| Publication status | Published - 2010 |
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Dive into the research topics of 'Physicochemical characterisation and drug release properties of celecoxib hot melt extruded glass solutions'. Together they form a unique fingerprint.Student theses
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Physicochemical characterization of solid dispersions prepared using hot-melt extrusion technology
Abu Diak, O. (Author), Andrews, G. (Supervisor) & Jones, D. (Supervisor), Dec 2009Student thesis: Doctoral Thesis › Doctor of Philosophy
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