The physicochemical characteristics of the injectable polymeric gels for use in the treatment of periodontal disease were investigated. The hardness, compressibility, and mucoadhesive properties of the gel were determined using a TA-XT2 Texture analyzer. The effect of of polymer concentration on the various viscoelastic, textural, bioadhesive properties and drug release were also analyzed using multifactorial analysis of variance. It was found that increased polymer concentration significantly increased gel structure, reduced polymer chain mobility and subsequently decreased the swelling/erosion and diffusion properties of the gel networks.
|Title of host publication||Transactions - 7th World Biomaterials Congress|
|Number of pages||1|
|Publication status||Published - 01 Jan 2004|
ASJC Scopus subject areas
Andrews, G. P., Jones, D. S., & Woolfson, A. D. (2004). Physicochemical characterisation of injectable polymeric gels for use in the treatment of periodontal disease. In Transactions - 7th World Biomaterials Congress (pp. 857)