Physicochemical characterisation of injectable polymeric gels for use in the treatment of periodontal disease

G.P. Andrews, D.S. Jones, A.D. Woolfson

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

Abstract

The physicochemical characteristics of the injectable polymeric gels for use in the treatment of periodontal disease were investigated. The hardness, compressibility, and mucoadhesive properties of the gel were determined using a TA-XT2 Texture analyzer. The effect of of polymer concentration on the various viscoelastic, textural, bioadhesive properties and drug release were also analyzed using multifactorial analysis of variance. It was found that increased polymer concentration significantly increased gel structure, reduced polymer chain mobility and subsequently decreased the swelling/erosion and diffusion properties of the gel networks.
Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages857
Number of pages1
Publication statusPublished - 01 Jan 2004

ASJC Scopus subject areas

  • Engineering(all)

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