Plasma concentrations of glucagon-like peptide-2 in adult patients with treated and untreated coeliac disease

Grant R Caddy; Joy E S Ardill; Davina Fillmore; Carolyn M Caldwell; Bronac M McKibben; Keith R Gardiner; Peter R G Watson

Plasma concentrations of glucagon-like peptide-2 in adult patients with treated and untreated coeliac disease

Grant R Caddy, Joy E S Ardill, Davina Fillmore, Carolyn M Caldwell, Bronac M McKibben, Keith R Gardiner, Peter R G Watson

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Coeliac disease is a common chronic inflammatory enteropathy characterized by villous atrophy and crypt hyperplasia in the small intestine. The mechanism of the intestinal damage in coeliac disease remains unclear. Glucagon-like peptide (GLP)-2 is an enterotrophic peptide that causes crypt hyperplasia and intestinal cell proliferation. We postulate that GLP-2 may be involved in the mucosal changes found in coeliac disease.

Original language	English
Pages (from-to)	195-202
Number of pages	8
Journal	EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Volume	18
Issue number	2
Publication status	Published - Feb 2006

ASJC Scopus subject areas

Gastroenterology

Cite this

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title = "Plasma concentrations of glucagon-like peptide-2 in adult patients with treated and untreated coeliac disease",

abstract = "Coeliac disease is a common chronic inflammatory enteropathy characterized by villous atrophy and crypt hyperplasia in the small intestine. The mechanism of the intestinal damage in coeliac disease remains unclear. Glucagon-like peptide (GLP)-2 is an enterotrophic peptide that causes crypt hyperplasia and intestinal cell proliferation. We postulate that GLP-2 may be involved in the mucosal changes found in coeliac disease.",

author = "Caddy, {Grant R} and Ardill, {Joy E S} and Davina Fillmore and Caldwell, {Carolyn M} and McKibben, {Bronac M} and Gardiner, {Keith R} and Watson, {Peter R G}",

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T1 - Plasma concentrations of glucagon-like peptide-2 in adult patients with treated and untreated coeliac disease

AU - Caddy, Grant R

AU - Ardill, Joy E S

AU - Fillmore, Davina

AU - Caldwell, Carolyn M

AU - McKibben, Bronac M

AU - Gardiner, Keith R

AU - Watson, Peter R G

PY - 2006/2

Y1 - 2006/2

N2 - Coeliac disease is a common chronic inflammatory enteropathy characterized by villous atrophy and crypt hyperplasia in the small intestine. The mechanism of the intestinal damage in coeliac disease remains unclear. Glucagon-like peptide (GLP)-2 is an enterotrophic peptide that causes crypt hyperplasia and intestinal cell proliferation. We postulate that GLP-2 may be involved in the mucosal changes found in coeliac disease.

AB - Coeliac disease is a common chronic inflammatory enteropathy characterized by villous atrophy and crypt hyperplasia in the small intestine. The mechanism of the intestinal damage in coeliac disease remains unclear. Glucagon-like peptide (GLP)-2 is an enterotrophic peptide that causes crypt hyperplasia and intestinal cell proliferation. We postulate that GLP-2 may be involved in the mucosal changes found in coeliac disease.

M3 - Article

C2 - 16394802

SN - 0954-691X

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SP - 195

EP - 202

JO - EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

JF - EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

IS - 2

ER -

Plasma concentrations of glucagon-like peptide-2 in adult patients with treated and untreated coeliac disease

Abstract

ASJC Scopus subject areas

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