Platinum catalysed hydrostannylation of terminal alkynes; highly selective synthesis of vinyl stannanes

Dean D. Roberts, Mark G. McLaughlin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
42 Downloads (Pure)

Abstract

We present the first study on the application of platinum complexes in the hydrostannylation of terminal alkynes. A range of platinum complexes were screened, with PtCl2/XPhos proving to provide the best selectivity for the β-(E)-vinyl stannane. The catalyst system is able to provide the corresponding vinyl stannane in selectivities which surpasses that which is typically afforded under palladium catalysis. Additionally, a telescoped hydrometallation/cross-coupling sequence has been developed, allowing for application of the vinyl stannanes without excessive manipulation or purification of the intermediate stannane.
Original languageEnglish
Pages (from-to) 1602-1606
JournalAdvanced Synthesis & Catalysis
Volume365
Issue number10
Early online date16 May 2023
DOIs
Publication statusPublished - 23 May 2023
Externally publishedYes

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