PMWS: Experimental model and co-infections

G. M. Allan; F. McNeilly; J. Ellis; S. Krakowka; A. Botner; K. McCullough; H. Nauwynck; S. Kennedy; B. Meehan; C. Charreyre

doi:10.1016/j.vetmic.2003.10.009

PMWS: Experimental model and co-infections

G. M. Allan^*, F. McNeilly, J. Ellis, S. Krakowka, A. Botner, K. McCullough, H. Nauwynck, S. Kennedy, B. Meehan, C. Charreyre

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

Porcine circovirus type 2 (PCV2) is now recognised as the causal agent of porcine multisystemic wasting syndrome (PMWS), an economically important wasting disease of young pigs [J. Vet. Diagn. Invest. 12 (2000) 3]. Gross lesions of PMWS include generalised lymphadenopathy, hepatitis, nephritis and pneumonia and typical histological lesions include lymphocytic depletion and multinucleated giant cell formation in lymph nodes, degeneration and necrosis of hepatocytes, and multifocal lymphohistocytic interstitial pneumonia. This communication will review the results of experimental infections of gnotobiotic (GN), colostrum-deprived (CD) and colostrum-fed (CF) pigs within our group, and elsewhere, with PCV2 and the conclusions that can be drawn from this work.

Original language	English
Pages (from-to)	165-168
Number of pages	4
Journal	Veterinary Microbiology
Volume	98
Issue number	2
DOIs	https://doi.org/10.1016/j.vetmic.2003.10.009
Publication status	Published - 04 Feb 2004
Externally published	Yes

Bibliographical note

Funding Information:
Some areas of this work were funded by Merial SAS and by the European Union (project No. GLK2-CT-1999-00445).

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

Keywords

Circovirus
Experimental infection
Porcine
Wasting

ASJC Scopus subject areas

Microbiology
General Veterinary

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.vetmic.2003.10.009

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title = "PMWS: Experimental model and co-infections",

abstract = "Porcine circovirus type 2 (PCV2) is now recognised as the causal agent of porcine multisystemic wasting syndrome (PMWS), an economically important wasting disease of young pigs [J. Vet. Diagn. Invest. 12 (2000) 3]. Gross lesions of PMWS include generalised lymphadenopathy, hepatitis, nephritis and pneumonia and typical histological lesions include lymphocytic depletion and multinucleated giant cell formation in lymph nodes, degeneration and necrosis of hepatocytes, and multifocal lymphohistocytic interstitial pneumonia. This communication will review the results of experimental infections of gnotobiotic (GN), colostrum-deprived (CD) and colostrum-fed (CF) pigs within our group, and elsewhere, with PCV2 and the conclusions that can be drawn from this work.",

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note = "Funding Information: Some areas of this work were funded by Merial SAS and by the European Union (project No. GLK2-CT-1999-00445). Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",

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doi = "10.1016/j.vetmic.2003.10.009",

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AU - Allan, G. M.

AU - McNeilly, F.

AU - Ellis, J.

AU - Krakowka, S.

AU - Botner, A.

AU - McCullough, K.

AU - Nauwynck, H.

AU - Kennedy, S.

AU - Meehan, B.

AU - Charreyre, C.

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AB - Porcine circovirus type 2 (PCV2) is now recognised as the causal agent of porcine multisystemic wasting syndrome (PMWS), an economically important wasting disease of young pigs [J. Vet. Diagn. Invest. 12 (2000) 3]. Gross lesions of PMWS include generalised lymphadenopathy, hepatitis, nephritis and pneumonia and typical histological lesions include lymphocytic depletion and multinucleated giant cell formation in lymph nodes, degeneration and necrosis of hepatocytes, and multifocal lymphohistocytic interstitial pneumonia. This communication will review the results of experimental infections of gnotobiotic (GN), colostrum-deprived (CD) and colostrum-fed (CF) pigs within our group, and elsewhere, with PCV2 and the conclusions that can be drawn from this work.

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PMWS: Experimental model and co-infections

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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