Polyacetals (and ketals) and polymers that contain acetal linkages in the main chain or in pendent chains are an important class of degradable polymer that can be considered for biomedical applications. While there are examples of polyacetals that have been used for orthopedic indications, recent years have seen a resurgence in research to efficiently prepare biocompatible polyacetal- and acetal-containing polymers. Polyacetals are currently being developed for potential biomedical use ranging from drug conjugation and formulation to consideration in regenerative medicine. This chapter describes recent work relating to polyacetal preparation and the range of biomedical applications that these polymers have been considered for.
|Title of host publication||Natural and Synthetic Biomedical Polymers|
|Number of pages||15|
|Publication status||Published - Jan 2014|
- Acid-labile degradation
- Nonacidic by-products
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)