Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer

K. Das, D.T. Leong, A. Gupta, L. Shen, T. Putti, G.S. Stein, A.J. Van Wijnen, Manuel Salto-Tellez

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Purpose: The runt-related transcription factor, Runx2 may have an oncogenic role in mediating metastatic events in breast cancer, but whether Runx2 has a role in the early phases of breast cancer development is not clear. We examined the expression of Runx2 and its relationship with oestrogen receptor (ER) and progesterone receptor (PR) in breast cancer cell lines and tissues.
Original languageEnglish
Pages (from-to)2239-2248
Number of pages10
JournalEuropean Journal of Cancer
Volume45
Issue number13
DOIs
Publication statusPublished - Sep 2009

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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