Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer

K. Das; D.T. Leong; A. Gupta; L. Shen; T. Putti; G.S. Stein; A.J. Van Wijnen; Manuel Salto-Tellez

doi:10.1016/j.ejca.2009.06.021

Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer

K. Das
, D.T. Leong
, A. Gupta
, L. Shen
, T. Putti
, G.S. Stein
, A.J. Van Wijnen
, Manuel Salto-Tellez

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

Purpose: The runt-related transcription factor, Runx2 may have an oncogenic role in mediating metastatic events in breast cancer, but whether Runx2 has a role in the early phases of breast cancer development is not clear. We examined the expression of Runx2 and its relationship with oestrogen receptor (ER) and progesterone receptor (PR) in breast cancer cell lines and tissues.

Original language	English
Pages (from-to)	2239-2248
Number of pages	10
Journal	European Journal of Cancer
Volume	45
Issue number	13
DOIs	https://doi.org/10.1016/j.ejca.2009.06.021
Publication status	Published - Sept 2009

ASJC Scopus subject areas

Cancer Research
Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ejca.2009.06.021

Cite this

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title = "Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer",

abstract = "Purpose: The runt-related transcription factor, Runx2 may have an oncogenic role in mediating metastatic events in breast cancer, but whether Runx2 has a role in the early phases of breast cancer development is not clear. We examined the expression of Runx2 and its relationship with oestrogen receptor (ER) and progesterone receptor (PR) in breast cancer cell lines and tissues.",

author = "K. Das and D.T. Leong and A. Gupta and L. Shen and T. Putti and G.S. Stein and \{Van Wijnen\}, A.J. and Manuel Salto-Tellez",

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T1 - Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer

AU - Das, K.

AU - Leong, D.T.

AU - Gupta, A.

AU - Shen, L.

AU - Putti, T.

AU - Stein, G.S.

AU - Van Wijnen, A.J.

AU - Salto-Tellez, Manuel

PY - 2009/9

Y1 - 2009/9

N2 - Purpose: The runt-related transcription factor, Runx2 may have an oncogenic role in mediating metastatic events in breast cancer, but whether Runx2 has a role in the early phases of breast cancer development is not clear. We examined the expression of Runx2 and its relationship with oestrogen receptor (ER) and progesterone receptor (PR) in breast cancer cell lines and tissues.

AB - Purpose: The runt-related transcription factor, Runx2 may have an oncogenic role in mediating metastatic events in breast cancer, but whether Runx2 has a role in the early phases of breast cancer development is not clear. We examined the expression of Runx2 and its relationship with oestrogen receptor (ER) and progesterone receptor (PR) in breast cancer cell lines and tissues.

U2 - 10.1016/j.ejca.2009.06.021

DO - 10.1016/j.ejca.2009.06.021

M3 - Article

SN - 0959-8049

VL - 45

SP - 2239

EP - 2248

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 13

ER -

Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer

Abstract

ASJC Scopus subject areas

UN SDGs

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