Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells

A J Jenkins; W Li; K Moller; R L Klein; M X Fu; J W Baynes; S R Thorpe; T J Lyons

Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells

A J Jenkins, W Li, K Moller, R L Klein, M X Fu, J W Baynes, S R Thorpe, T J Lyons

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

We determined whether pre-enrichment of low density lipoproteins (LDL) with alpha-tocopherol mitigates their adverse effects, following in vitro glycation, oxidation or glycoxidation, towards cultured bovine retinal capillary endothelial cells (RCEC) and pericytes.

Original language	English
Pages (from-to)	137-45
Number of pages	9
Journal	Current eye research
Volume	19
Issue number	2
Publication status	Published - Aug 1999

Keywords

Animals
Capillaries
Cattle
Cell Count
Cells, Cultured
Drug Combinations
Endothelin-1
Glycosylation
Humans
Lipoproteins, LDL
Nitrites
Oxidation-Reduction
Plasminogen Activator Inhibitor 1
Proteins
Retinal Vessels
Vitamin E

Cite this

@article{f62c3c0564d34b2a8c071348ca47b4c3,

title = "Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells",

abstract = "We determined whether pre-enrichment of low density lipoproteins (LDL) with alpha-tocopherol mitigates their adverse effects, following in vitro glycation, oxidation or glycoxidation, towards cultured bovine retinal capillary endothelial cells (RCEC) and pericytes.",

keywords = "Animals, Capillaries, Cattle, Cell Count, Cells, Cultured, Drug Combinations, Endothelin-1, Glycosylation, Humans, Lipoproteins, LDL, Nitrites, Oxidation-Reduction, Plasminogen Activator Inhibitor 1, Proteins, Retinal Vessels, Vitamin E",

author = "Jenkins, {A J} and W Li and K Moller and Klein, {R L} and Fu, {M X} and Baynes, {J W} and Thorpe, {S R} and Lyons, {T J}",

year = "1999",

month = aug,

language = "English",

volume = "19",

pages = "137--45",

journal = "Current eye research",

issn = "0271-3683",

publisher = "Taylor and Francis",

number = "2",

}

TY - JOUR

T1 - Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells

AU - Jenkins, A J

AU - Li, W

AU - Moller, K

AU - Klein, R L

AU - Fu, M X

AU - Baynes, J W

AU - Thorpe, S R

AU - Lyons, T J

PY - 1999/8

Y1 - 1999/8

N2 - We determined whether pre-enrichment of low density lipoproteins (LDL) with alpha-tocopherol mitigates their adverse effects, following in vitro glycation, oxidation or glycoxidation, towards cultured bovine retinal capillary endothelial cells (RCEC) and pericytes.

AB - We determined whether pre-enrichment of low density lipoproteins (LDL) with alpha-tocopherol mitigates their adverse effects, following in vitro glycation, oxidation or glycoxidation, towards cultured bovine retinal capillary endothelial cells (RCEC) and pericytes.

KW - Animals

KW - Capillaries

KW - Cattle

KW - Cell Count

KW - Cells, Cultured

KW - Drug Combinations

KW - Endothelin-1

KW - Glycosylation

KW - Humans

KW - Lipoproteins, LDL

KW - Nitrites

KW - Oxidation-Reduction

KW - Plasminogen Activator Inhibitor 1

KW - Proteins

KW - Retinal Vessels

KW - Vitamin E

M3 - Article

C2 - 10420183

SN - 0271-3683

VL - 19

SP - 137

EP - 145

JO - Current eye research

JF - Current eye research

IS - 2

ER -

Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells

Abstract

Keywords

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