Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations

Paul A McCarron; Diarmaid J Murphy; Claire Little; Julie McDonald; Oonagh J Kelly; Mark G Jenkins

doi:10.1111/j.1553-2712.2011.01032.x

Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations

Paul A McCarron, Diarmaid J Murphy, Claire Little, Julie McDonald, Oonagh J Kelly, Mark G Jenkins

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The aim of this study was to assess a novel semisolid material as a potential topical drug delivery system for acute laceration. The objectives were to correlate physical characterization data using rheologic studies and to compare with clinical assessment of performance in an emergency department (ED).

Original language	English
Pages (from-to)	333-9
Number of pages	7
Journal	Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Volume	18
Issue number	4
DOIs	https://doi.org/10.1111/j.1553-2712.2011.01032.x
Publication status	Published - Apr 2011

Bibliographical note

Keywords

Lacerations
Young Adult
Drug Delivery Systems
Chemistry, Pharmaceutical
Humans
Aged
Pilot Projects
Borates
Emergency Service, Hospital
Anesthetics, Local
Polyvinyl Alcohol
Aged, 80 and over
Adult
Treatment Outcome
Middle Aged
Adolescent
Male
Administration, Topical
Female
Anesthesia, Local

Access to Document

10.1111/j.1553-2712.2011.01032.x

Cite this

McCarron, P. A., Murphy, D. J., Little, C., McDonald, J., Kelly, O. J., & Jenkins, M. G. (2011). Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 18(4), 333-9. https://doi.org/10.1111/j.1553-2712.2011.01032.x

@article{758288150c9f44669f1a80e60b65fbfd,

title = "Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations",

abstract = "The aim of this study was to assess a novel semisolid material as a potential topical drug delivery system for acute laceration. The objectives were to correlate physical characterization data using rheologic studies and to compare with clinical assessment of performance in an emergency department (ED).",

keywords = "Lacerations, Young Adult, Drug Delivery Systems, Chemistry, Pharmaceutical, Humans, Aged, Pilot Projects, Borates, Emergency Service, Hospital, Anesthetics, Local, Polyvinyl Alcohol, Aged, 80 and over, Adult, Treatment Outcome, Middle Aged, Adolescent, Male, Administration, Topical, Female, Anesthesia, Local",

author = "McCarron, {Paul A} and Murphy, {Diarmaid J} and Claire Little and Julie McDonald and Kelly, {Oonagh J} and Jenkins, {Mark G}",

note = "{\textcopyright} 2011 by the Society for Academic Emergency Medicine.",

year = "2011",

month = apr,

doi = "10.1111/j.1553-2712.2011.01032.x",

language = "English",

volume = "18",

pages = "333--9",

journal = "Academic emergency medicine : official journal of the Society for Academic Emergency Medicine",

issn = "1553-2712",

publisher = "Wiley-Blackwell",

number = "4",

}

McCarron, PA, Murphy, DJ, Little, C, McDonald, J, Kelly, OJ & Jenkins, MG 2011, 'Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations', Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, vol. 18, no. 4, pp. 333-9. https://doi.org/10.1111/j.1553-2712.2011.01032.x

Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations. / McCarron, Paul A; Murphy, Diarmaid J; Little, Claire et al.
In: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, Vol. 18, No. 4, 04.2011, p. 333-9.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations

AU - McCarron, Paul A

AU - Murphy, Diarmaid J

AU - Little, Claire

AU - McDonald, Julie

AU - Kelly, Oonagh J

AU - Jenkins, Mark G

PY - 2011/4

Y1 - 2011/4

N2 - The aim of this study was to assess a novel semisolid material as a potential topical drug delivery system for acute laceration. The objectives were to correlate physical characterization data using rheologic studies and to compare with clinical assessment of performance in an emergency department (ED).

AB - The aim of this study was to assess a novel semisolid material as a potential topical drug delivery system for acute laceration. The objectives were to correlate physical characterization data using rheologic studies and to compare with clinical assessment of performance in an emergency department (ED).

KW - Lacerations

KW - Young Adult

KW - Drug Delivery Systems

KW - Chemistry, Pharmaceutical

KW - Humans

KW - Aged

KW - Pilot Projects

KW - Borates

KW - Emergency Service, Hospital

KW - Anesthetics, Local

KW - Polyvinyl Alcohol

KW - Aged, 80 and over

KW - Adult

KW - Treatment Outcome

KW - Middle Aged

KW - Adolescent

KW - Male

KW - Administration, Topical

KW - Female

KW - Anesthesia, Local

U2 - 10.1111/j.1553-2712.2011.01032.x

DO - 10.1111/j.1553-2712.2011.01032.x

M3 - Article

C2 - 21496134

SN - 1553-2712

VL - 18

SP - 333

EP - 339

JO - Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

JF - Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

IS - 4

ER -

McCarron PA, Murphy DJ, Little C, McDonald J, Kelly OJ, Jenkins MG. Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2011 Apr;18(4):333-9. doi: 10.1111/j.1553-2712.2011.01032.x

Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations

Abstract

Bibliographical note

Keywords

Access to Document

Fingerprint

Cite this